VELVET LONGEVITY™
Epigenetic Longevity Peptide Concentrate
Rewrite your skin's age.
Price
$248
Size
20 ml / 0.68 fl oz
The world's first cosmetic concentrate targeting three epigenetic longevity pathways simultaneously — progerin clearance (Progeline™), stem cell self-renewal (Reproage™), and SIRT1/SIRT6 sirtuin activation (Epigen 32) — for skin that behaves younger at the cellular level.
Three epigenetic longevity pathways: progerin clearance (Progeline™) + stem cell renewal (Reproage™) + sirtuin activation (Epigen 32)
Clears progerin — the nuclear aging protein that causes structural skin collapse
Restores epidermal stem cell self-renewal via Wnt/β-catenin pathway reactivation
Activates SIRT1 and SIRT6 longevity genes — the same sirtuins activated by caloric restriction
Visibly firms and lifts skin in 28 days via nuclear envelope remodelling
PM-only intensive treatment: use 3–4 evenings per week
The most premium and scientifically advanced SKU in the VELPEPTIDE™ lineup
Clinical Results Timeline
What to Expect
Week 1–2
Skin feels denser and more resilient. Subtle improvement in surface texture.
Week 3–4
Visible improvement in skin firmness. Sagging along jawline begins to lift.
Week 5–8
Measurable increase in skin density. Deep wrinkles visibly reduced. Skin appears structurally younger.
Week 9–12
Full epigenetic remodelling visible. Skin behaves like skin 5–10 years younger in clinical photography.
VELVET LONGEVITY™ is the most scientifically advanced product in the VELPEPTIDE™ lineup — and the only cosmetic concentrate in the world targeting three independent epigenetic longevity pathways simultaneously. (1) Progeline™ (Tripeptide-10 Citrulline, Lucas Meyer/IFF): clears progerin, the toxic protein that accumulates in fibroblast nuclei with age and causes structural collapse of the nuclear envelope, skin sagging, and loss of elasticity. Progelin clearance is the mechanism behind the Werner syndrome model of accelerated aging — VELVET LONGEVITY™ targets the same pathway in normal skin. (2) Reproage™ (Acetyl Tetrapeptide-22, Givaudan): restores epidermal stem cell self-renewal capacity by reactivating the Wnt/β-catenin pathway, which declines with age and causes the epidermis to thin and lose regenerative capacity. (3) Epigen 32 (Acetyl Tetrapeptide-9, Lipotec/Lubrizol): activates SIRT1 and SIRT6 longevity genes — the same sirtuins activated by caloric restriction and NAD+ supplementation — directly in skin cells, triggering a cellular metabolic shift toward repair and longevity. All three mechanisms are additive and target different molecular structures. Use 3–4 evenings per week as an intensive longevity treatment, after VELVET FIRM™ and before VELVET LIFT™.
| INCI Name | Common Name | Benefit | Concentration |
|---|---|---|---|
| Aqua | Water | Solvent base | — |
| Tripeptide-10 Citrulline | Progeline™ (Lucas Meyer / IFF) | Progerin-clearing peptide (Lucas Meyer Cosmetics / IFF) — targets and clears progerin, the truncated form of Lamin A that accumulates in fibroblast nuclei with age, causing nuclear envelope collapse, loss of skin elasticity, and structural sagging. Clinically proven: 30% reduction in progerin expression in 28 days; 20% increase in skin firmness. INCI-listed, CIR-reviewed, IECIC-confirmed globally. | 3% |
| Acetyl Tetrapeptide-22 | Reproage™ (Givaudan) | Epidermal stem cell renewal peptide (Givaudan Active Beauty) — reactivates the Wnt/β-catenin signalling pathway in epidermal stem cells, restoring their self-renewal capacity that declines with age; clinically proven to increase epidermal stem cell density and restore skin regenerative capacity; INCI-listed, IECIC-confirmed globally. | 3% |
| Acetyl Tetrapeptide-9 | Epigen 32 (Lipotec / Lubrizol) | Sirtuin-activating peptide (Lipotec/Lubrizol) — activates SIRT1 and SIRT6 longevity genes in skin cells, triggering a cellular metabolic shift toward repair, autophagy, and longevity; the same sirtuins activated by caloric restriction and NAD+ supplementation; clinically proven to reduce wrinkle depth and improve skin density; INCI-listed, IECIC-confirmed globally. | 3% |
| Lactobacillus Ferment Lysate | Postbiotic Amplifier (Givaudan) | Postbiotic peptide amplifier — upregulates longevity peptide receptor expression by up to 60%, amplifying the efficacy of Progeline™, Reproage™, and Epigen 32. INCI-listed, CIR-reviewed, IECIC-confirmed. Globally compliant. | 3% |
| Copper Tripeptide-1 (Liposomal) | GHK-Cu Liposome 10% | Carrier peptide pre-encapsulated in liposomes — activates 4,000+ repair genes including those involved in collagen, elastin, and glycosaminoglycan synthesis; synergistic with Epigen 32 sirtuin activation for comprehensive cellular repair | 2% |
| Palmitoyl Tripeptide-38 (Liposomal) | Matrixyl Synthe'6® Liposome | Signal peptide in phospholipid liposome — simultaneously stimulates 6 key matrix proteins: collagen I, III, IV, fibronectin, hyaluronic acid, and laminin-5; liposomal delivery ensures sustained overnight matrix synthesis | 2% |
| Sodium Hyaluronate | Hyaluronic Acid (Multi-Weight) | Multi-molecular weight complex for deep hydration and plumping across all skin layers | 2% |
| Squalane | Squalane | Barrier repair and emollient; mimics skin's own sebum for non-comedogenic overnight nourishment | 5% |
| Ceramide NP | Ceramide NP | Restores epidermal lipid matrix; supports barrier function during intensive treatment | 2% |
| Tocopherol | Vitamin E | Antioxidant protection against oxidative stress during cellular repair | 1% |
| Panthenol | Pro-Vitamin B5 | Soothing, barrier repair, anti-inflammatory | 2% |
| Phenoxyethanol | Preservative | Preservation | 0.9% |
Complete the Ritual
