Triple-Pathway Brightening Peptide Essence
Three brightening pathways. Zero irritation.
Price
$128
Size
30 ml / 1.01 fl oz
The only brightening serum targeting three independent melanogenesis pathways — MITF gene inhibition (Brightenyl®), MC1R receptor blockade (Melanostatine™ 5), and melanin transfer inhibition (Oligopeptide-34) — with Chronodyn® AM circadian activation and postbiotic amplifiers.
Triple-pathway brightening: MITF gene inhibition (Brightenyl®) + MC1R receptor blockade (Melanostatine™ 5) + melanin transfer inhibition (Oligopeptide-34)
Fades hyperpigmentation and dark spots in 14 days
4× more potent than Vitamin C for brightening (Brightenyl®)
Blocks melanin production at the gene level — upstream of tyrosinase
Melanostatine™ 5 blocks the MC1R receptor — stops the melanin signal before it starts
Oligopeptide-34 inhibits melanin transfer via PAR-2 pathway
Chronodyn® AM circadian sync — brightening aligned with peak melanin-suppression window
Postbiotic amplifier increases brightening receptor expression by up to 60%
Suitable for all skin tones including melanin-rich skin
Clinical Results Timeline
Week 1–2
Skin appears more radiant and even. Dark spots begin to fade at the edges.
Week 3–4
Measurable reduction in melanin concentration. Skin tone visibly more uniform.
Week 5–8
Significant fading of post-inflammatory hyperpigmentation and sun damage.
Week 9–12
Sustained luminosity and near-complete fading of superficial dark spots.
VELVET GLOW™ 2026 is the only brightening serum targeting three independent melanogenesis pathways simultaneously: (1) MITF gene inhibition via SPP-conjugated Brightenyl® (Givaudan) — blocks melanin production at the gene level before tyrosinase is even produced, 4× more potent than Vitamin C; (2) MC1R receptor blockade via Melanostatine™ 5 (Nonapeptide-1, Lucas Meyer/IFF) — acts as an antagonist of the melanocyte-stimulating hormone receptor, stopping the melanin signal before it reaches the MITF pathway; and (3) melanin transfer inhibition via Oligopeptide-34 — blocks the PAR-2 pathway that transfers melanosomes from melanocytes to keratinocytes, preventing dark spot formation even when some melanin is produced. All three mechanisms are additive and target different points in the melanogenesis cascade. Chronodyn® AM activates BMAL1 to synchronise brightening delivery with the skin's peak melanin-suppression window. Lactobacillus Ferment Lysate postbiotic amplifier upregulates receptor expression by up to 60%.
| INCI Name | Common Name | Benefit | Concentration |
|---|---|---|---|
| Aqua | Water | Solvent base | — |
| Lactobacillus Ferment Lysate | Postbiotic Amplifier (Givaudan) | Postbiotic peptide amplifier — upregulates MITF-inhibition receptor expression in melanocytes by up to 60%, amplifying Brightenyl®'s gene-level brightening effect. INCI-listed, CIR-reviewed, IECIC-confirmed. Globally compliant. | 3% |
| Tripeptide-10 Citrulline (and) Chronodyn® | Chronodyn® (Sederma/Croda) | Chronobiological activator — activates BMAL1 gene expression to synchronise brightening delivery with the skin's peak AM melanin-suppression window. Fully INCI-listed, Sederma EU-approved, IECIC-confirmed globally. | 1% |
| Diglucosyl Gallic Acid (SPP-Conjugated) | Brightenyl® (Givaudan) — SPP-Enhanced | Patented bio-boosted brightening active (Givaudan Active Beauty) — inhibits MITF transcription to block tyrosinase production at the gene level before melanin synthesis begins; 4× more potent than Vitamin C; activated by the skin's own microbiome for sustained brightening; globally approved across EU, US, India, China, Japan, and Korea | 3% |
| Nonapeptide-1 | Melanostatine™ 5 (Lucas Meyer / IFF) | MC1R receptor antagonist (Lucas Meyer Cosmetics / IFF) — biomimetic of alpha-MSH; blocks the melanocyte-stimulating hormone receptor (MC1R) directly, preventing the melanin signal from reaching the MITF pathway; upstream of both MITF inhibition and tyrosinase inhibition; clinically proven on Asian skin; INCI-listed, CIR-reviewed, IECIC-confirmed globally | 2% |
| Oligopeptide-34 | Oligopeptide-34 (PAR-2 Inhibitor) | Dual-mechanism brightening peptide — inhibits tyrosinase activity AND blocks the PAR-2 pathway that transfers melanosomes from melanocytes to keratinocytes, preventing dark spot formation even when some melanin is produced; additive to Brightenyl® and Melanostatine™ 5; INCI-listed, IECIC-confirmed globally | 1% |
| Ascorbyl Glucoside | Stabilized Vitamin C | Antioxidant and brightening; ferulic acid-stabilized for maximum potency | 2% |
| Niacinamide | Vitamin B3 | Inhibits melanosome transfer from melanocytes to keratinocytes; brightening and barrier support | 5% |
| Alpha-Arbutin | Alpha-Arbutin | Gentle tyrosinase inhibitor; synergistic with Brightenyl® for comprehensive melanin suppression — formulated at 1.8% (below EU 2% limit per Regulation 2024/996; safety margin maintained). Zero free Hydroquinone impurity confirmed by HPLC assay (India CDSCO compliance). | 1.8% |
| Copper Tripeptide-1 (Liposomal) | GHK-Cu Liposome 10% | Carrier peptide pre-encapsulated in liposomes — activates superoxide dismutase and 4,000+ repair genes; neutralises UV-induced free radicals; 7× greater cellular absorption vs. free GHK-Cu; supports collagen and elastin synthesis alongside brightening actives | 1% |
| Sodium Hyaluronate | Hyaluronic Acid | Hydration and plumping | 1% |
| Glycerin | Glycerin | Humectant | 4% |
| Panthenol | Pro-Vitamin B5 | Soothing, healing | 2% |
| Ferulic Acid | Ferulic Acid | Antioxidant booster; stabilises Vitamin C and amplifies efficacy | 0.5% |
| Phenoxyethanol | Preservative | Preservation | 0.9% |
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